Buy Generic Neurontin (Gabapentin) Online – More Details You Should Know

What is Neurontin?

Neurontin, known by its generic name gabapentin, is a pharmaceutical medication that belongs to the class of anticonvulsant drugs. It is specifically designed to help manage and control seizures in individuals with epilepsy. However, Neurontin is not limited to just one use. Its versatile nature allows it to be prescribed for a range of conditions, including neuropathic pain, restless legs syndrome, and even certain psychiatric disorders.

It operates by altering the activity of calcium channels in the central nervous system, resulting in a decrease in the release of certain excitatory neurotransmitters. This modulation helps to regulate abnormal neuronal firing and may contribute to its anticonvulsant and analgesic properties. Additionally, it influences the availability of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter that promotes a calming effect on the brain.

Classification

Neurontin (gabapentin) is classified as an anticonvulsant or antiepileptic medication. Anticonvulsants are a class of drugs primarily used to manage seizures and prevent their recurrence. While Neurontin was initially developed and approved for the treatment of epilepsy, it has also shown efficacy in other conditions such as neuropathic pain and certain psychiatric disorders. Additionally, this drug may be used off-label for various indications, but its primary classification remains as an anticonvulsant.

What is neurontin generic name?

The generic name for Neurontin is gabapentin. Gabapentin is an anticonvulsant medication that is structurally related to the neurotransmitter gamma-aminobutyric acid (GABA). It is thought to work by modulating calcium channels and increasing the availability of GABA, an inhibitory neurotransmitter, in the central nervous system. Gabapentin is commonly prescribed for the treatment of seizures, neuropathic pain, and other conditions as determined by healthcare professionals. It may be available in various formulations, such as capsules, tablets, or oral solution.

What is Neurontin used for?

Neurontin (gabapentin) is prescribed for various medical conditions and can be used to manage different symptoms. Some of the common cases in which it may be prescribed include:

1. Epilepsy: Neurontin is FDA-approved for the treatment of partial seizures and as an adjunctive therapy for generalized seizures in adults and children aged 3 years and older.
2. Neuropathic Pain: Neurontin is commonly prescribed for the management of neuropathic pain conditions, such as diabetic neuropathy, postherpetic neuralgia (pain following shingles), and peripheral neuropathy.
3. Fibromyalgia: Neurontin may be prescribed as an off-label treatment for fibromyalgia, a chronic pain disorder characterized by widespread musculoskeletal pain, fatigue, and tender points.
4. Restless Legs Syndrome (RLS): This drug can be used off-label to alleviate the uncomfortable sensations and urge to move associated with RLS, a neurological disorder affecting the legs.
5. Migraine Prevention: Neurontin may be prescribed off-label for the prevention of migraines, particularly in individuals who experience frequent or severe migraine attacks.
6. Anxiety Disorders: In certain cases, Neurontin may be prescribed off-label to help manage symptoms of anxiety disorders, such as generalized anxiety disorder (GAD) and social anxiety disorder (SAD).
7. Off-Label Uses: Neurontin is sometimes prescribed off-label for other conditions, including bipolar disorder, alcohol withdrawal, trigeminal neuralgia, and certain psychiatric disorders.

How does Neurontin work?

Here is a list outlining the mechanism of action of Neurontin (gabapentin):

1. Modulation of Calcium Channels: It exerts its effects by binding to a specific subunit (α2δ-1) of calcium channels in the central nervous system. This binding reduces the influx of calcium ions into neurons, leading to a decrease in the release of various excitatory neurotransmitters.
2. Inhibition of Excitatory Neurotransmitter Release: By inhibiting the release of excitatory neurotransmitters, such as glutamate, this medication helps to dampen abnormal neuronal activity. This mechanism contributes to its antiepileptic and analgesic properties.
3. Increased GABA Availability: This drug increases the concentration of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. This enhanced availability of GABA helps to further reduce neuronal excitability and promote a calming effect.
4. Altered Neurotransmitter Signaling: The very product affects various neurotransmitters involved in pain perception, including norepinephrine and substance P. By modulating their release and signaling pathways, it may provide relief from neuropathic pain.
5. Attenuation of Central Sensitization: Neurontin may prevent or reduce central sensitization, a process where the central nervous system becomes more sensitive to pain signals over time. By inhibiting abnormal neuronal firing and modulating pain pathways, Neurontin can help mitigate this phenomenon.

How long does it take Neurontin to work?

The onset of action of Neurontin (gabapentin) can vary among individuals and depends on several factors. While some individuals may experience relief from symptoms relatively quickly, for others, it may take some time for the medication to exert its therapeutic effects.

The mechanism of action involves modulating certain neurotransmitters in the brain, specifically targeting the calcium channels. By doing so, it aims to reduce abnormal neuronal firing and dampen the transmission of pain signals. However, the precise time it takes for Neurontin to work can differ from person to person.

In some cases, individuals may notice an improvement in their symptoms within a few days or weeks of starting the treatment. This could manifest as a reduction in pain intensity, a decrease in seizure frequency, or an improvement in neuropathic symptoms. However, it’s essential to note that the therapeutic effects may continue to develop over an extended period.

How long does Neurontin stay in your system?

The duration of time that Neurontin (gabapentin) remains in the body can vary among individuals. On average, Neurontin has a half-life of approximately 5 to 7 hours in adults with normal kidney function. A medication’s half-life refers to the time it takes for half of the drug to be eliminated from the body.

Based on the half-life of Neurontin, it can take approximately 1 to 2 days for the medication to be completely eliminated from the body after discontinuation. However, it’s important to note that individual factors such as metabolism, kidney function, and dosage may influence how long Neurontin stays in the system.

What is the dosage?

Dosage Strength	Minimum Dosage	Maximum Dosage	Frequency of Administration
100 mg Capsules	100 mg	2,400 mg	Typically taken 3 times a day
300 mg Capsules	300 mg	3,600 mg	Typically taken 3 times a day
400 mg Capsules	400 mg	3,600 mg	Typically taken 3 times a day
600 mg Tablets	600 mg	3,600 mg	Typically taken 3 times a day
800 mg Tablets	800 mg	3,600 mg	Typically taken 3 times a day
Oral Solution	Varies	Varies	Typically taken 3 times a day

Overdose

The symptoms of a Neurontin overdose may include:

1. Central Nervous System Depression: Excessive sedation, drowsiness, confusion, dizziness, impaired coordination, and difficulty speaking or slurred speech.
2. Respiratory Depression: Shallow or slowed breathing, shortness of breath, or difficulty breathing.
3. Cardiovascular Effects: Fluctuations in blood pressure, rapid or irregular heartbeat, or changes in heart rate.
4. Gastrointestinal Disturbances: Nausea, vomiting, diarrhea, or abdominal discomfort.
5. Changes in Mental State: Agitation, restlessness, hallucinations, delirium, or seizures (especially in individuals not previously prone to seizures).

If an overdose is suspected, it is crucial to seek immediate medical attention. In the meantime, you can take the following steps:

1. Do not induce vomiting unless instructed to do so by a healthcare professional or poison control center.
2. If the individual is unconscious or having difficulty breathing, call emergency services for assistance and perform basic life support measures, such as CPR, if necessary.
3. Provide relevant information to the medical professionals, such as the amount of Neurontin ingested (if known), the time of ingestion, and any other medications or substances taken.
4. Follow the guidance and recommendations of healthcare professionals for treatment, which may include activated charcoal administration, monitoring of vital signs, and supportive care.

What are contraindications?

Here’s a list of contraindications for Neurontin (gabapentin):

1. Hypersensitivity: This drug should not be used in individuals who have a known hypersensitivity or allergy to gabapentin or any of its components.
2. Severe Renal Impairment: The described product is primarily eliminated through the kidneys, so caution is advised in individuals with severe renal impairment (creatinine clearance less than 30 mL/min). Dosage adjustments may be necessary in such cases.
3. Pediatric Use: It is not recommended for use in children younger than 3 years old for the treatment of epilepsy. The safety and effectiveness of Neurontin in other pediatric populations for different indications may vary and should be determined by a healthcare professional.

What are the side effects?

Common Side Effects	Rare Side Effects
Fatigue	Confusion
Dizziness	Suicidal thoughts or behavior
Drowsiness	Worsening of depression
Headache	Changes in mood or behavior
Tremor	Allergic reactions
Nausea	Swelling of the face, lips,
	tongue, or throat
Vomiting	Severe skin rash or blistering
Dry mouth	Difficulty breathing or swallowing
Constipation	Chest pain or rapid heartbeat
Weight gain	Yellowing of the skin or eyes
Peripheral edema (swelling)	Unusual bleeding or bruising
Balance problems	Changes in sexual desire or
	performance
Coordination difficulties

What are drug interactions?

Here is a list of potential drug interactions with Neurontin:

1. Antacids: Some antacids containing aluminum or magnesium hydroxide can reduce the absorption of Neurontin. It is advisable to separate the administration of Neurontin and antacids by at least 2 hours.
2. Opioids: Concurrent use of Neurontin with opioids may increase the risk of central nervous system (CNS) depression and respiratory depression. Caution and close monitoring are recommended when using these medications together.
3. Sedatives and Benzodiazepines: Combining Neurontin with sedatives or benzodiazepines can result in increased CNS depression and drowsiness. Extra caution and careful monitoring are advised when using these drugs concurrently.
4. Alcohol: Alcohol consumption can enhance the sedative effects of Neurontin, potentially leading to increased drowsiness and impaired motor coordination. It is generally recommended to avoid or limit alcohol intake while taking Neurontin.
5. Antidepressants: Certain antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), may interact with Neurontin and increase the risk of CNS-related side effects.
6. Antiepileptic Drugs (AEDs): Combining Neurontin with other AEDs may require dosage adjustments and careful monitoring, as interactions can occur that affect the blood levels and effectiveness of these medications.
7. Drug Metabolism Inhibitors and Inducers: Some drugs that inhibit or induce the metabolism of Neurontin may impact its blood levels and effectiveness. Examples include cimetidine (inhibitor) and phenytoin (inducer).
8. Diuretics: Certain diuretics may reduce the excretion of Neurontin, potentially leading to increased blood levels. Dose adjustments or monitoring may be necessary in these cases.
9. Antacids for Stomach Ulcers: Neurontin absorption may be reduced when taken with antacids used to treat stomach ulcers, such as sucralfate. It is recommended to separate the administration of these medications.
10. Morphine: Neurontin may increase the exposure to morphine when taken together, potentially leading to an increased risk of morphine-related side effects. Close monitoring is advised in such cases.

What are withdrawal symptoms?

Common withdrawal symptoms associated with Neurontin discontinuation include:

1. Rebound Symptoms: The return or worsening of the condition being treated with Neurontin, such as seizures or neuropathic pain, may occur upon sudden cessation.
2. Anxiety: Some individuals may experience increased anxiety, restlessness, or feelings of unease during withdrawal.
3. Insomnia: Difficulties with sleep initiation or maintenance may be observed, leading to disrupted sleep patterns.
4. Mood Changes: Withdrawal from Neurontin can cause mood swings, irritability, agitation, or depression in certain individuals.
5. Nausea and Digestive Upset: Gastrointestinal symptoms like nausea, vomiting, diarrhea, or stomach discomfort may occur during the withdrawal process.
6. Physical Discomfort: Headaches, muscle aches, tremors, or flu-like symptoms can manifest during the withdrawal.

Gabapentin vs Neurontin

Gabapentin and Neurontin are essentially the same medication, with Neurontin being the brand name for gabapentin. Gabapentin is the active ingredient in Neurontin.

When a medication is first developed, it is typically given a generic name based on its active ingredient. In the case of gabapentin, it is the generic name. Once a pharmaceutical company develops and markets the medication, they assign a brand name to it for marketing purposes. Neurontin is the brand name that was given to gabapentin by Pfizer, the original manufacturer.

The primary difference between gabapentin and Neurontin is the name itself. Both medications contain the same active ingredient and are chemically identical. The efficacy, safety, and potential side effects of gabapentin and Neurontin are expected to be the same, as they are essentially interchangeable.

Neurontin pricing

Please keep in mind that the following historical rates for Neurontin (gabapentin) are approximate and can vary depending on factors such as location, dosage strength, formulation, and time period. These rates are not current and should be used for reference purposes only.

• In the early 2000s, the average wholesale price (AWP) for a 90-capsule supply of Neurontin 300mg ranged from approximately $180 to $220.
• By the mid-2000s, the AWP for a 90-capsule supply of Neurontin 300mg decreased to approximately $120 to $150.
• In the late 2000s to early 2010s, the AWP for a 90-capsule supply of Neurontin 300mg further declined to around $80 to $110.
• As generic versions of gabapentin became available, the prices for generic Neurontin significantly decreased. The AWP for a 90-capsule supply of generic gabapentin 300mg ranged from approximately $20 to $40 in the mid-2010s.

FAQs

Q: Why is Neurontin a controlled substance?

A: Neurontin (gabapentin) is not classified as a controlled substance by the U.S. Drug Enforcement Administration (DEA). However, it is worth noting that in some states, there has been increased scrutiny and regulation surrounding the prescribing and dispensing of gabapentin due to concerns of potential misuse or abuse.

While Neurontin itself is not classified as a controlled substance, it can still have effects that may be desirable to certain individuals. It has been observed that some individuals may misuse or abuse Neurontin to enhance the effects of other substances or to achieve a euphoric high. This has led to increased monitoring and regulations in some areas to help prevent such misuse.

The potential for misuse or abuse is not unique to this medication, as it can occur with various medications and substances. However, it’s important to emphasize that it is generally considered to have a lower risk of abuse compared to controlled substances like opioids or benzodiazepines.

Q: Neurontin for dogs – yes or no?

A: Neurontin (gabapentin) is occasionally prescribed for dogs by veterinarians, depending on the specific condition being treated. While this drug is primarily approved for human use, its off-label use in veterinary medicine has been observed for certain situations.

In veterinary practice, it may be prescribed to dogs for the management of certain types of pain, particularly neuropathic pain or chronic pain conditions. It may also be used as an adjunctive treatment in dogs with epilepsy or seizures that are not adequately controlled by other medications.

It’s important to note that the use of Neurontin in dogs requires veterinary guidance and supervision. The dosage, duration of treatment, and considerations for the dog’s specific health condition should be carefully evaluated by a veterinarian. Dogs may respond differently to medications compared to humans, and the veterinarian will take into account factors such as the dog’s breed, size, age, and overall health status when determining the appropriateness of Neurontin.

Q: Is neurontin a good painkiller?

A: Neurontin (gabapentin) can be an effective pain management option for certain individuals and specific types of pain. While Neurontin is not classified as a traditional opioid-based painkiller, it has shown efficacy in alleviating certain types of chronic pain, particularly neuropathic pain.

Neuropathic pain, often described as a burning, shooting, or tingling sensation, occurs due to nerve damage or dysfunction. The mechanism of action targets the transmission of pain signals in the central nervous system, helping to reduce the intensity and frequency of neuropathic pain.

Q: Does neurontin make you sleepy?

A: Neurontin (gabapentin) can have sedative effects and may cause drowsiness in some individuals. The medication has the potential to induce a calming and relaxing effect, leading to feelings of sleepiness or fatigue.

For certain individuals, Neurontin’s sedative properties can be beneficial, especially when managing conditions such as anxiety disorders or insomnia. The calming effect may help promote better sleep quality and facilitate the onset of sleep.

Q: Neurontin and alcohol

A: It is important to exercise caution when considering the interaction between Neurontin (gabapentin) and alcohol. Both Neurontin and alcohol can have central nervous system depressant effects, and combining them can potentially enhance these effects, leading to increased sedation, drowsiness, and impaired motor coordination.

Drinking alcohol while taking gabapentin can intensify the sedative properties of the medication, potentially leading to excessive drowsiness and reduced cognitive function. This combination may impair judgment and coordination, making activities such as driving or operating machinery unsafe.

Additionally, alcohol can also increase the risk of certain side effects, such as dizziness, drowsiness, and difficulty concentrating. It may also contribute to potential respiratory depression, especially at higher doses or in individuals with underlying respiratory conditions.

Q: Does neurontin cause weight gain?

A: Weight gain is a potential side effect that has been reported by some individuals taking Neurontin (gabapentin). While not everyone experiences weight gain while using this drug, it is important to be aware of this possibility.

The exact mechanisms behind Neurontin-induced weight gain are not fully understood. However, it is believed that this medication may influence appetite and metabolism, potentially leading to increased food intake and decreased energy expenditure. Additionally, changes in fluid retention and body composition have also been suggested as contributing factors.

Neurontin reviews

John S: Neurontin has been a game-changer for me. As someone who suffered from chronic neuropathic pain, this medication has brought me relief like no other. I can finally enjoy life without being constantly held back by the discomfort.

Emily G: Neurontin has been my trusted companion in managing my epilepsy. Thanks to this medication, my seizures have significantly reduced, allowing me to focus on my daily activities and pursue my passions without constant worry.

Mark R: Living with fibromyalgia was incredibly challenging until I discovered Neurontin. It has become an essential part of my treatment regimen, providing me with much-needed relief from the widespread pain and allowing me to regain control of my life.

Sarah H: Neurontin has been a true lifesaver for my restless legs syndrome. Before starting this medication, I would have sleepless nights filled with uncomfortable sensations. Now, thanks to Neurontin, I can finally enjoy a peaceful and uninterrupted sleep.

David M: Dealing with postherpetic neuralgia after shingles was unbearable until Neurontin came into my life. This medication has made a remarkable difference, easing the intense pain and allowing me to fully recover and regain my quality of life.

Jessica B: Neurontin has been an incredible ally in my battle against migraines. With its help, I’ve experienced a significant reduction in the frequency and intensity of my headaches. I can now better enjoy each day without the constant fear of a debilitating migraine attack.

Ryan W: Neurontin has made a world of difference for my anxiety disorder. The medication has helped calm my racing thoughts and physical symptoms, allowing me to face challenging situations with a greater sense of calm and control.

Lauren K: As a patient with multiple sclerosis, Neurontin has been a vital component of my treatment plan. It has effectively alleviated the neuropathic pain associated with my condition, enabling me to maintain an active lifestyle and focus on the things I love.

Michael P: Neurontin has been a key player in managing my chronic pain after spinal surgery. It has significantly reduced the discomfort, allowing me to engage in physical therapy and regain my strength more effectively.

Ashley R: Neurontin has been a true blessing for my son, who has epilepsy. Since starting this medication, his seizures have become less frequent, giving him the opportunity to live a more normal and fulfilling life. We are incredibly grateful for Neurontin’s positive impact on his well-being.

Disclaimer:The information provided on this website is for informational purposes only and is not intended as medical advice. The product is a prescription medication and should only be taken under the supervision of a qualified healthcare provider. This info is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice. Always consult with a qualified healthcare provider before starting or stopping any medication or if you have any questions or concerns about your health.