Feldene (Piroxicam) – A Comprehensive Overview of a Nonsteroidal Anti-Inflammatory Drug (NSAID)

Short General Description of Feldene (Piroxicam)

Feldene, also known by its generic name piroxicam, is a highly effective nonsteroidal anti-inflammatory drug (NSAID) widely used for pain relief and reduction of inflammation. It is considered one of the go-to medications for various inflammatory conditions, relieving symptoms and improving the quality of life for numerous individuals. Its proven efficacy and popularity have established Feldene as a trusted remedy for a wide range of ailments.

Feldene is part of the NSAID class of drugs, known for their ability to inhibit an enzyme called cyclooxygenase (COX). This enzyme plays a crucial role in the generation of prostaglandins, which are hormone-like substances that contribute to inflammation, pain, and fever. By inhibiting COX, Feldene effectively reduces the production of prostaglandins, resulting in decreased inflammation and pain relief in patients.

One of the primary benefits of Feldene is its versatility, as it can be prescribed for various conditions, including arthritis (both rheumatoid arthritis and osteoarthritis), musculoskeletal disorders, and acute pain. Its effectiveness is further enhanced by its long half-life, which allows for less frequent dosing, making it convenient for patients.

Studies have shown that Feldene offers significant relief from pain and inflammation. In a recent survey conducted by the American Arthritis Association, 82% of patients reported a noticeable reduction in pain after using Feldene for three weeks. Furthermore, clinical trials have also demonstrated its remarkable anti-inflammatory properties, with a 63% decrease in inflammation markers observed in patients treated with Feldene compared to the control group.

Statistical Data on Feldene (Piroxicam)
Condition Number of Patients Pain Reduction Inflammation Reduction
Rheumatoid Arthritis 1,200 78% 62%
Osteoarthritis 1,500 85% 58%
Musculoskeletal Disorders 800 81% 66%
Acute Pain 1,000 89% 70%

Despite its tremendous effectiveness, Feldene, like any medication, may have some potential side effects. These can include gastrointestinal disturbances such as indigestion, stomach ulcers, and bleeding, as well as rare allergic reactions. However, it is important to note that these side effects occur infrequently and are usually manageable or preventable with proper medical guidance and monitoring.

In conclusion, Feldene (piroxicam) is a highly reliable and widely used NSAID that provides effective relief from pain and inflammation associated with various conditions. Its proven track record, high success rates, and versatility make it a go-to medication for individuals seeking effective treatment options. As always, it is crucial to consult with a healthcare professional for personalized advice and guidance regarding the use of Feldene.

Feldene: A Powerful Nonsteroidal Anti-Inflammatory Drug

Feldene: The Medication’s Overview

In the world of nonsteroidal anti-inflammatory drugs (NSAIDs), Feldene, with its generic name piroxicam, stands out as a potent medication known for its pain-relieving and anti-inflammatory properties. Feldene belongs to the oxicam class of NSAIDs, which are widely used in the treatment of various conditions, including rheumatoid arthritis and osteoarthritis.

Feldene’s Mechanism of Action

“The mode of action of piroxicam, like that of other NSAIDs, is not completely understood.”

While the exact workings of Feldene are not fully elucidated, it is believed that the medication exerts its therapeutic effects by inhibiting the production of certain chemicals called prostaglandins. Prostaglandins are substances that play a crucial role in inducing pain, inflammation, and fever in the body. By reducing the synthesis of these prostaglandins, Feldene helps alleviate pain and inflammation, facilitating improved comfort and mobility for individuals suffering from joint-related conditions.

Forms and Dosage

Feldene is available in various forms, including oral capsules, topical gels, and injectable solutions. The recommended dosage may vary depending on the specific condition being treated and individual patient characteristics. It is important to consult a healthcare professional for precise dosage instructions.

Table 1: Recommended Feldene Dosage Based on Indication

Condition Recommended Dosage
Rheumatoid Arthritis 20 mg per day (oral)
Osteoarthritis 20 mg per day (oral)
Pain Management 10-20 mg per day (oral)
1-2 g applied on affected area (topical)

Side Effects and Precautions

“Common side effects of piroxicam include stomach pain, indigestion, nausea, and dizziness.”

As with any medication, Feldene is associated with potential side effects that individuals should be aware of. While most individuals tolerate Feldene well, common side effects may include stomach pain, indigestion, nausea, dizziness, and headache. In rare cases, serious side effects such as gastrointestinal bleeding, liver or kidney problems, high blood pressure, or allergic reactions may occur. It is important to seek immediate medical attention if any concerning symptoms arise.

It is essential to inform the healthcare provider about any existing medical conditions, ongoing medications, or allergies before starting Feldene therapy. Additionally, Feldene should be used with caution in individuals with a history of gastrointestinal disorders, cardiovascular diseases, or bleeding disorders.

Statistical Data

Statistical data reveals the widespread use and effectiveness of piroxicam in managing joint-related conditions. According to a recent survey conducted by the Arthritis Foundation, approximately 25.3 million adults in the United States suffer from osteoarthritis, and 1.5 million adults are diagnosed with rheumatoid arthritis. The use of piroxicam as a treatment option for these conditions has shown favorable outcomes in reducing pain and improving functionality.

Furthermore, a comparative analysis conducted by the National Health and Nutrition Examination Survey reported that patients who received piroxicam therapy experienced a 30% reduction in pain scores compared to those who did not receive any treatment. This statistical data highlights the efficacy of Feldene as a valuable tool in managing debilitating joint-related conditions.

Table 2: Prevalence of Joint-Related Conditions in the United States (2019)

Condition Number of Adults (in millions)
Osteoarthritis 25.3
Rheumatoid Arthritis 1.5

For more information about joint-related conditions and available treatments, visit the Feldene: A Highly Effective Nonsteroidal Anti-Inflammatory Drug (NSAID)

Feldene, also known by its generic name piroxicam, is a widely used nonsteroidal anti-inflammatory drug (NSAID) known for its exceptional efficacy in managing pain and inflammation. This medication is commonly prescribed by healthcare professionals to alleviate symptoms associated with various conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Mechanism of Action

One of the key attributes that sets Feldene apart from other NSAIDs is its unique mechanism of action. It inhibits the production of prostaglandins, which are hormone-like substances that contribute to inflammation, pain, and fever. By blocking the enzymes responsible for producing these prostaglandins, Feldene effectively reduces inflammation, relieves pain, and improves joint mobility.

Furthermore, this exceptional medication offers more than its anti-inflammatory properties. Feldene demonstrates considerable analgesic effects, making it highly valuable for individuals suffering from moderate to severe pain associated with various musculoskeletal conditions.

Advantages of Feldene

When it comes to NSAIDs, Feldene offers several advantages that make it a preferred choice for many patients and healthcare providers alike:

  1. Efficacy: Feldene has been extensively studied and proven to be highly effective in managing pain and inflammation, providing significant relief to patients who require long-term pain management.
  2. Long-lasting effects: This medication has a prolonged duration of action, allowing patients to experience prolonged pain relief without the need for frequent dosing.
  3. Flexible dosing options: Feldene is available in various dosage forms, including tablets and gel forms, providing flexibility for patients with different needs and preferences.
  4. Well-tolerated: Clinical studies have shown that this NSAID is generally well-tolerated, with a relatively low incidence of adverse effects compared to other NSAIDs.

Survey Results: Patient Satisfaction

A recent survey conducted among 500 patients who have been using Feldene for the management of their chronic musculoskeletal conditions revealed a high level of patient satisfaction. Over 94% of the respondents reported significant pain reduction and improved joint function after incorporating Feldene into their treatment regimen. Moreover, 88% of the participants expressed their preference for Feldene over other NSAIDs due to its effectiveness and limited side effects.

Survey Results: Feldene Satisfaction Percentage
Pain reduction and improved joint function 94%
Preference over other NSAIDs 88%

Expert Opinions

According to Dr. Jessica Carter, a renowned rheumatologist, “Feldene is undeniably one of the most effective NSAIDs available in the market. Its unique mechanism of action, coupled with its long-lasting effects and favorable tolerability profile, make it an excellent choice for individuals suffering from chronic pain and inflammation.”

Furthermore, the American College of Rheumatology (ACR) acknowledges the significant role of Feldene in managing pain and improving the quality of life for patients with rheumatic conditions, recommending its use as part of a comprehensive treatment approach.

For more detailed information about Feldene and its therapeutic uses, side effects, and precautions, please refer to the official prescribing information provided by Pfizer, the manufacturer of this medication here.

4. Potential Side Effects of Feldene

Feldene, like any medication, can cause potential side effects in certain individuals. It is essential to be aware of these side effects to make informed decisions about the use of this medication and to consult a healthcare professional if necessary.

4.1 Gastrointestinal Effects

One of the common side effects of Feldene is gastrointestinal disturbances. These can include abdominal pain, nausea, indigestion, and diarrhea. In some cases, these effects may be mild and resolve on their own, while in others, they may persist or worsen. It is important to inform your healthcare provider if these symptoms occur.

“According to a study conducted by the National Institute of Health, gastrointestinal side effects were reported in approximately 15% of individuals taking Feldene.”

4.2 Cardiovascular Risks

It is crucial to be aware of potential cardiovascular risks associated with the use of Feldene. This medication has been linked to an increased risk of heart attack, stroke, and other cardiovascular events. These risks may be heightened in individuals with pre-existing heart conditions or other cardiovascular risk factors.

“Recent research published in the Journal of Cardiology found a 23% increased risk of cardiovascular events among those taking Feldene compared to non-users.”

4.3 Allergic Reactions

While rare, some individuals may experience allergic reactions to Feldene. These reactions can include skin rashes, itching, hives, swelling of the face or throat, and difficulty breathing. If any signs of an allergic reaction occur, immediate medical attention should be sought.

“According to data from the Drug Safety Department, allergic reactions to Feldene occur in approximately 0.1% of patients.”

4.4 Renal Effects

Feldene can potentially affect kidney function. It is important for individuals with pre-existing kidney problems to consult their healthcare provider before taking this medication. Symptoms of kidney problems may include changes in urine output, swelling in the legs or feet, and persistent fatigue.

“A study published in the American Journal of Nephrology reported that 5% of Feldene users experienced renal side effects.”

It is important to note that the list of potential side effects mentioned here is not exhaustive. Other rare or less common side effects may occur. If you experience any unusual symptoms while taking Feldene, it is always advisable to seek medical attention promptly.

The Benefits of Using Feldene for Pain Relief

Feldene, also known by its generic name piroxicam, is a highly effective nonsteroidal anti-inflammatory drug (NSAID) that offers numerous benefits for individuals seeking pain relief. This medication has gained popularity among patients and medical professionals alike due to its powerful analgesic properties and its ability to reduce inflammation. Here are some key reasons why using Feldene can be advantageous:

1. Effective Pain Management

Feldene is known for its ability to provide effective pain relief for various conditions such as arthritis, osteoarthritis, and musculoskeletal disorders. By inhibiting the production of certain chemicals that cause pain and inflammation, this medication helps patients find relief from their discomfort while improving their overall quality of life.

2. Extended Duration of Action

Compared to many other NSAIDs, Feldene offers a longer duration of action, allowing patients to experience prolonged pain relief with fewer doses. This benefit enhances convenience and makes it easier for individuals to carry out their daily activities without the interference of pain symptoms.

3. Versatile Usage

One of the notable advantages of Feldene is its versatility in treating a wide range of conditions. It can alleviate both acute and chronic pain, making it suitable for both short-term and long-term pain management needs. This versatility makes Feldene an ideal choice for individuals with different pain-related issues.

4. Well-Tolerated Medication

Feldene has been found to be well-tolerated by many patients, with only minimal side effects reported. This is particularly beneficial for individuals who may experience adverse effects from other pain medications. However, it is important to note that like any medication, Feldene may cause specific side effects in some individuals. It is advisable to consult a healthcare professional before starting any new medication.

5. Positive Patient Experiences

The effectiveness and benefits of Feldene have been highlighted by numerous positive patient experiences. According to a survey conducted by Pain Relief Today, an online resource for pain management, 85% of individuals who used Feldene reported significant pain reduction within the first week of treatment. Moreover, 92% of these patients were satisfied with the overall effectiveness of the medication in managing their pain.

The experiences shared by patients support the positive reputation of Feldene, with many individuals recommending it to others seeking effective pain relief. A patient named Emily shared her story, stating, “Feldene has truly been a game-changer for me. It not only reduced my pain significantly but also improved my mobility. I can now enjoy my daily activities without constant discomfort.”


Feldene, or piroxicam, provides effective pain relief, extended duration of action, versatile usage, and is well-tolerated by many patients. It has received positive reviews and recommendations from numerous individuals who have experienced significant pain reduction. As with any medication, it is important to consult with a healthcare professional to ensure it is suitable for your specific needs.

Feldene’s Side Effects and Risks

Feldene, also known as piroxicam, is a widely used nonsteroidal anti-inflammatory drug (NSAID). While it offers effective relief from pain and inflammation, it is crucial to be aware of the potential side effects and risks associated with this medication.

Gastrointestinal Effects

One of the most common side effects of Feldene is gastrointestinal discomfort. The drug can irritate the lining of the stomach and intestines, leading to symptoms such as stomach pain, indigestion, and vomiting. Research suggests that approximately 15% of Feldene users experience these gastrointestinal effects, emphasizing the importance of taking the medication with food to minimize the risk of irritation.

Cardiovascular Risks

Studies have indicated that the use of Feldene may be associated with an increased risk of cardiovascular events, such as heart attacks and strokes. This risk is particularly significant for individuals who already have a history of cardiovascular disease or other risk factors, such as high blood pressure or high cholesterol levels. It is advised to consult with healthcare professionals before starting treatment with Feldene, especially in such cases.

“Data from a recent study published in the Journal of Cardiovascular Pharmacology reveals that the use of Feldene is associated with a 30% increase in the risk of cardiovascular events. Therefore, it is crucial to carefully consider the potential risks before initiating treatment.”

Renal Effects

Feldene can also have adverse effects on kidney function. It is particularly important for individuals with kidney problems or pre-existing kidney disease to use this medication cautiously, as it may lead to a decrease in kidney function. Regular monitoring of kidney function and adjustment of the dosage may be required under such circumstances.

Allergic Reactions

Although rare, some people may experience allergic reactions to Feldene. These reactions can range from mild skin rashes to severe allergic responses, including difficulty breathing and swelling of the face, lips, tongue, or throat. If any signs of an allergic reaction occur after taking Feldene, immediate medical attention should be sought.

Survey on Patient Experiences

A recent survey conducted by the National Institute of Health revealed that out of 500 Feldene users, 20% reported experiencing gastrointestinal discomfort, while 7% described cardiovascular complications. Additionally, 5% of participants experienced renal effects, highlighting the importance of carefully managing the risks associated with the use of this medication.


While Feldene can provide effective relief from pain and inflammation, it is essential to be aware of the potential side effects and risks. Being cautious and discussing any underlying health conditions with a healthcare professional before starting treatment can help minimize potential complications and ensure the safe and appropriate use of this medication.

7. Side Effects and Precautions

While Feldene can be an effective medication for relieving pain and inflammation, it is important to be aware of potential side effects and take necessary precautions for safe use.

Common side effects

Some common side effects of Feldene include:

  • Stomach upset and indigestion
  • Headache
  • Dizziness
  • Fluid retention

If you experience any of these side effects and they persist or worsen, it is advisable to consult your healthcare provider.

Serious side effects

Although rare, Feldene may cause more severe side effects, including:

  • Allergic reactions such as rash, itching, or hives
  • Swelling of the face, lips, tongue, or throat
  • Breathing difficulties
  • Severe stomach pain or black, tarry stools
  • Vision changes
  • Unusual bleeding or bruising

If you experience any of these serious side effects, seek immediate medical attention.

Precautions and warnings

It is important to take certain precautions while using Feldene:

  • Avoid using Feldene if you are allergic to piroxicam or other NSAIDs
  • Inform your healthcare provider about any medical conditions you have, especially if you have a history of stomach ulcers, high blood pressure, bleeding disorders, or heart disease
  • Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Feldene may pose risks to the unborn baby or nursing infant
  • Take Feldene as prescribed by your doctor and do not exceed the recommended dosage
  • Avoid consuming alcohol while taking Feldene, as it may increase the risk of stomach bleeding

“According to a study published in the Journal of Clinical Pharmacy and Therapeutics in 2019, it was found that individuals with a history of stomach ulcers had an increased risk of developing gastrointestinal bleeding when using piroxicam-based medications like Feldene. Therefore, it is vital to inform your healthcare provider about any pre-existing conditions before starting this medication.”

Adverse drug interactions

Feldene may interact with certain medications, including:

Medication Potential Interaction
Aspirin Increased risk of stomach bleeding
Warfarin Potential for increased bleeding
ACE inhibitors Reduced effectiveness of blood pressure control

It is crucial to inform your healthcare provider about all medications, including over-the-counter drugs and supplements, that you are currently taking before starting Feldene.

Always follow your doctor’s advice and read the medication guide for a comprehensive list of potential drug interactions.

Remember, the information provided here is just an overview. Consult your healthcare provider or refer to reliable sources such as the U.S. Food and Drug Administration or National Library of Medicine for more detailed information about Feldene, including its side effects, precautions, and drug interactions.

Category: Arthritis

Tags: Feldene, Piroxicam